Francesca Zito
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0916809549 Orcid |
Francesca
Zito
Institute for Biomedical Research and Innovation Researcher Nutrheff Thematic Biological validation
Research Interest and expertise in the field of nutraceuticals
and functional food
Keywords: Inflammation, immunomodulation, gene expression, cytokines, toxicity, anti-oxidant effect
Nutraceuticals and foods of interestIdentification of the anti-inflammatory/antioxidant effects of Zingiber officinale (ginger), a tropical plant used as a spice, on cells in vitro. We demonstrated that 6-gingerol, one of the main component of ginger, at high doses, had a toxic effect on immune cells of P. lividus sea urchin. At the same time, 6-gingerol, at low doses, had an immunomodulatory effect, influencing the expression of immune genes. Other studies are in progress on the effect of ginger total extract on murine cells. Zingiber officinale (ginger) Fields of application biology and medicine Facilities and equipments Cell culture sterile room and equipment; Optical, brightfield and fluorescence microscopes; PCR and Quantitative-PCR instruments; Instruments for analysis of proteins and nucleic acids; Instruments for assays in luminometry and fluorimetry |
