Alessandra Camarca
EMail+39-0825-299304 Orcid Scholar WOS Scopus |
Alessandra
Camarca
Institute of Food Science Research Nutrheff Thematic Biological validation
Research Interest and expertise in the field of nutraceuticals
and functional food
Keywords: Immune-modulation, Peripheral blood mononuclear cells (PBMCs), T cell lines (TCLs), Gluten, Intestinal Inflammation
Nutraceuticals and foods of interestInterest in mucosal immunology and celiac disease. Expertise in gluten-specific T cell lines, identification of gluten immunogenic peptides and alternative cereals, validation of strategies for gluten detoxification. Evaluation of the immune-modulatory properties of biomolecules by ex-vivo analysis on human peripheral blood mononuclear cells (cell proliferation/vitality, pro- and anti-inflammatory cytokines production, expression of activation markers, differentiation of dendritic cells). Bioactive peptides, polyphenols and probiotics/prebiotics, from vegetable extracts and/or from food-derived microorganisms. Fields of application Characterization of alternative cereals for celiac disease patients diet; characterization of novel gluten endopetidases; identification of novel anti-inflammatory natural compounds. Facilities and equipments Tools for in vitro expansion and culturing of primary intestinal gluten-specific T cell lines. Tools for isolation, ex-vivo culturing and analysis of human peripheral blood mononuclear cells. Equipment for cellular immunology assays such as ELISA, proliferation, cytofluorimetric analysis. |
