Cristina Sobacchi
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Cristina
Sobacchi
Institute for Genetic and Biomedical Research Senior Researcher Nutrheff Thematic Biomolecular technologies (enzymatic, biochemical, molecular biology), Biological validation
Research Interest and expertise in the field of nutraceuticals
and functional food
Keywords: Terpene, essential oils, skeletal disease, bone loss, molecular mechanism, oxidative stress, Wnt signaling
Nutraceuticals and foods of interestBioactive compounds acting on skeletal metabolism (mainly antioxidant stress response and Wnt signaling) and potentially useful to treat bone loss. Compounds could be tested in vitro and in vivo in relevant animal models. This research interest is shared with Dr E. Palagano (IBBR, Florence). Complementary expertise and equipment allow moving from the isolation and characterization of bioactive compounds to their assessment under conditions of increasing complexity and relevance for human disease Aromatic plants and essential oils Fields of application Food supplements, bone health, skeletal diseases, bone loss Facilities and equipments Animal facility: standard tools; 2-photon microscope, IVI Lumina II Imaging System for bioluminescence/fluorescence studies, IVIS XGI-8 gas anesthesia system, SARRP irradiator, Mythic18VET hemocytometer. Histology Lab. Unit of Advanced Optical Microscopy: confocal, fluorescence, and optical microscopes; Laser Scanning Microscopy DMI8 Super Resolution instrument. Genomic Unit: NextSeq Illumina sequencers, 10x Genomics instrument, AB 3500DX Genetic Analyzer. Flow Cytometry Core: FACS stations, BD FACSymphonyTM, FACSAriaIIITM. |
