Luigia Cristino
EMail39 081 867 5134 (office)/5105 (Lab) Home Page Orcid Scholar Researchgate WOS Scopus |
Luigia
Cristino
Institute of Biomolecular Chemistry - CNR Senior Researcher, Ph.D. Nutrheff Thematic Validazione biologica - Studi clinico-nutrizionali - Comunicazione ed iniziative promozionali
Research Interest and expertise in the field of nutraceuticals
and functional food
Keywords: brain, synapse, obesity, cell metabolism, aging neurogenesis,cannabinoids
Nutraceuticals and foods of interestin vivo mouse model and in vitro (cells) morphofunctional studies of the effect on brain functioning, neurogenesis, aging, addictive and compulsive behaviors, and energy homeostasis. Identification and characterization of biomolecular mechanisms regulating the antinflammatory effects of nutraceuticals and functional foods on the cell metabolism of neurons and glia at level of synaptic plasticity, in physiological and pathological conditions. (endo)cannabinoids-like molecules and microbiota-derived endocannabinoid-like metabolites affecting the brain via gut-brain axis Fields of application Neuroscience, Cell biology,Metabolism, Physiology; Medicinal Chemistry, Food Sciences; Facilities and equipments Facility of Time lapse Live Cell Microscopy for functional, cellular and subcellular imaging of glia and neurons in brain slices and colture microscopy. Light, confocal and electron microscopy. Electrophysiology and optogenetics . Immunocytochemistry and immunohistochemistry. Mouse colony of diabetic, obese and trasngenic mice moled of neuorodegeneartion for in vivo study based on administration of diet supplemented with specific nutraceuticals of functionalized foods |
